CNSP Archives - TinyGems

MondayOct 27, 2025 10:00 am

Scientists Uncover Possible Driver of ‘Chemo Brain’

A recent study has found that the cognitive difficulties which cancer patients experience during and after treatment could stem from chemotherapy-induced damage to the brain's waste drainage network. Newly discovered evidence sheds light on a widespread yet poorly understood phenomenon that affects up to 75% of individuals undergoing cancer therapy, chemo brain. The symptoms associated with this condition, including memory lapses and problems with concentration and finding words, typically persist long after treatment is complete. Published in the journal Communications Biology, the study examined how common cancer drugs impact meningeal lymphatics, specialized vessels within the brain membranes responsible for waste…

MondayOct 13, 2025 10:00 am

New AI Tool Boosts Precision Medicine in Treating CNS Cancers

Harvard Medical School researchers have developed an AI system that distinguishes glioblastoma from other brain tumors during surgery. The tool called PICTURE achieved 99.8% accuracy in differentiating glioblastoma from primary central nervous system lymphoma. This rare malignancy is frequently misdiagnosed as glioblastoma, yet the AI system outperformed nine human neuropathologists who misclassified lymphoma as glioblastoma in 38% of test cases. With over 100 distinct subtypes, central nervous system tumors involve exceptional diagnostic complexity. Glioblastoma represents the most common variety, with patients typically receiving surgical tumor removal but facing a median survival of just eight months. Primary CNS lymphoma shares overlapping…

TuesdaySep 02, 2025 10:00 am

Study Finds Link Between Head Injuries and Elevated Brain Cancer Risk

A recent study conducted at Mass General Brigham has found a potential link between head injuries and an elevated risk of developing brain cancer. The researchers analyzed data collected from over 75,000 people with traumatic brain injuries that ranged from mild to severe between 2000 and 2024, and discovered that patients with a history of suffering traumatic brain injury (TBI) were more likely to develop malignant brain tumors compared to patients who had not experienced traumatic brain injuries in the past. Sometimes referred to as intracranial injuries, TBIs occur when external mechanical forces such as rapid deceleration or acceleration, shock…

MondayAug 11, 2025 10:00 am

Study Reveals Potential Way to Treat Pediatric Gliomas

A joint study between the Broad Institute and the Dana-Farber Cancer Institute has discovered a new and potentially effective way to treat pediatric gliomas. The research revealed that a percentage of children diagnosed with gliomas, an incredibly common type of pediatric brain cancer, may respond to certain inhibitors that have already been approved by the U.S. Food and Drug Administration. According to the researchers, 8.9% of pediatric glioma patients exhibited fibroblast growth factor receptor alterations, a group of proteins that play a key role in cell differentiation, growth, and development. These alterations increased the gliomas’ sensitivity to inhibitors that can…

MondayJul 21, 2025 10:00 am

New Machine Learning Model Predicts Cancer Severity, Aids Treatment Planning

A joint team of Polish and Brazilian researchers has developed a new machine learning model that can help improve cancer treatment planning by accurately predicting cancer severity. The model uses machine learning technology to identify specific proteins in tumor cells and predict how aggressive the tumors will be, allowing physicians to tailor cancer treatments for their patients. With cancer diagnoses increasing globally, the medical industry is eager for tools that improve diagnosis and treatment. This model represents some of the most cutting-edge efforts to gain deeper insight into tumor development. As machine learning and artificial intelligence grow more advanced by…

WednesdayJun 25, 2025 10:00 am

New Scanning Method Could Improve How Brain Tumors are Treated

Researchers from NHS Grampian and the University of Aberdeen have been granted funding to study a novel scanning method that could improve how physicians scan and treat brain tumors. The Scottish Government awarded the research team nearly $470,000 in funding to investigate new means of treating glioblastomas, an aggressive brain tumor that affects tens of thousands of Americans each year. Glioblastomas are responsible for 48% of brain tumors in the primary malignant class and are estimated to take 10,000 American lives each year. The Chief Scientist Office Translational Clinical Studies grant will enable the research team to generate entirely unique…

WednesdayApr 23, 2025 10:00 am

Study Identifies Key Enzyme That Could Be Targeted to Fight Brain Cancers

Researchers at Ohio State University Medical Center have identified a key enzyme that may be used to combat one of the deadliest types of brain cancer. Known as PGM3, this enzyme plays a critical role in the hexosamine biosynthesis pathway, which contributes to rapid tumor growth through protein and lipid glycosylation. Targeting PGM3 could significantly improve glioblastoma treatment outcomes. Glioblastomas are highly malignant tumors that typically form in the brain or spinal cord. They spread rapidly from their onset, causing increased intracranial pressure and symptoms such as headaches, nausea, drowsiness, blurred vision, seizures, and personality changes. These tumors are particularly…

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