CLDI Archives - TinyGems

WednesdayOct 22, 2025 10:00 am

Study Suggests mRNA Covid Vaccine Could Boost Cancer Immunotherapy

New research published at the European Society for Medical Oncology conference on Sunday has revealed that the mRNA coronavirus vaccine could have an unintended benefit: boosting immunotherapy effectiveness. Although the research is still in its initial phases, experts say Covid vaccines may be able to improve immune function during immunotherapy and make the treatment more potent. Immunotherapy is a relatively new cancer treatment that uses a patient's immune system to fight tumor cells, avoiding the side effects typically associated with chemotherapy and radiation. The connection between coronavirus vaccines and improved immunotherapy efficacy will be explored further in a Phase 3…

WednesdayOct 08, 2025 10:00 am

Researchers Discover Why Cancer Immunotherapy Could Be Failing

A new study from Ohio State University Wexner Medical Center has discovered why immunotherapy fails in 60-80% of cancer patients. Researchers identified a previously unknown stress pathway called TexPSR that floods weakened immune cells with misfolded proteins, crippling their ability to attack tumors. Blocking this pathway in laboratory models restored immune cell function and significantly improved immunotherapy effectiveness across multiple cancer types. Immune system T cells recognize and fight infections and cancer, but often become weakened and lose effectiveness during prolonged battles with tumors. The Ohio State team found these depleted T cells collapse under misfolded proteins that trigger TexPSR,…

WednesdaySep 17, 2025 10:00 am

How Patients Can Boost Dietary Nutrient Intake During Cancer Treatment

Cancer treatment creates a cruel irony for patients: just when their bodies need more nutrients to fight the disease and recover from treatment, eating becomes one of the biggest challenges they face. Chemotherapy, radiation, and other cancer treatments can turn favorite foods into unpalatable options while simultaneously increasing the body's nutritional demands, putting cancer patients in a difficult position. Sarah Washburn, a dietitian with UCLA's cancer center, sees this struggle daily among her patients. Treatment side effects wreak havoc on taste buds, appetite, and digestion, making proper nutrition feel like an uphill battle when patients are already fighting for their…

WednesdayJul 16, 2025 10:00 am

Study Suggests Herpes Virus Can Be Modified to Fight Advanced Melanoma

Findings from a recent study suggest that the herpes virus can be modified into an effective treatment for some types of advanced melanoma. Conducted by researchers from the University of Southern California's Keck Medicine of USC, the clinical trial looked into the feasibility of deploying cancer-fighting herpes virus against advanced skin cancers. When researchers used a genetically engineered herpes simplex virus and combined it with immunotherapy, they found that the combination could reduce or completely destroy advanced melanoma tumors in 30% of the patients involved in the clinical trial. The clinical trial’s findings indicate that the herpes simplex virus, which…

MondayJun 02, 2025 10:00 am

Korean Researchers Develop AI to Predict Cancer Patients’ Response to Immunotherapy

A research team whose leadership is based in South Korea has developed an AI model for predicting how cancer patients will respond to immunotherapy. Designed to improve the precision of treatment in colorectal and gastric cancer, the AI model could provide physicians with a significantly more accurate tool for customizing therapies. Immunotherapy is a relatively new approach to cancer treatment that involves “training” the immune system to recognize and destroy malignant cells. In contrast to chemotherapy and radiation which can damage surrounding healthy tissue, immunotherapy allows physicians to more precisely target tumor cells. As a result, many patients undergoing immunotherapy…

MondayMay 12, 2025 10:00 am

Getting a Second Opinion After Breast Cancer Diagnosis Doesn’t Delay Treatment Commencement

It is very natural to feel immense anxiety and fear after receiving a breast cancer diagnosis. Most people don't consider seeking second opinions and would rather begin treatment right away. After all, breast cancer is one of the deadliest types of cancer in women, second only to lung cancer in terms of fatalities. The Breast Cancer Research Foundation estimates that slightly over 42,000 women will die from the condition in 2025, making it one of the most prolific killers in the USA. However, researchers say that getting a second opinion after the first breast cancer diagnosis does not delay the…

MondayMar 31, 2025 10:00 am

Natural Killer Cells That are Genetically Modified Show Potential in Cancer Immunotherapy

Under normal circumstances, natural killer cells in the body can detect and eliminate malignant cells. However, these NK cells can at times be unable to breach the defense mechanisms of tumors, rendering the killer cells unable to combat the growing cancer. A recent pre-clinical study suggests that natural killer cells can be tweaked in a bid to boost their ability to fight cancerous cells. This study’s findings appeared in the Nature Immunology journal and the work was a collaborative effort between several universities and companies. These included Pompeu Fabra University, Karolinska Institutet located in Sweden, a Germany-based company called Miltenyi…

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