Blocking Fructose Metabolism Boosts Immune Response to Childhood Cancer
Researchers at Johns Hopkins may have found a new approach to group 3 medulloblastoma, a deadly and hard-to-treat pediatric brain cancer. Mouse experiments suggest that disrupting how tumor cells generate energy can slow the disease. The research was conducted at the Kimmel Cancer Center and published in Acta Neuropathologica Communications. Group 3 medulloblastoma is one of the most difficult pediatric brain cancers to treat, and effective therapies remain scarce. The new research reveals how tumor cells rewire their energy production to fuel rapid growth. It also shows that interfering with those processes can slow the disease. Senior author Ranjan Perera, Ph.D., of Johns Hopkins All Children's Hospital, said the work points toward a largely unexplored therapeutic avenue. According…

