Rogue Rings of DNA Expose Brain Tumor Secrets
International researchers have identified a surprising culprit behind glioblastoma's devastating lethality: circular DNA fragments that operate independently from normal chromosomes. These genetic renegades may hold the key to understanding why this brain cancer kills most patients within fourteen months despite decades of medical advances. The discovery challenges conventional thinking about how cancer develops. Rather than emerging after tumors establish themselves, these circular DNA elements appear to orchestrate malignancy from the very beginning, with some patients showing evidence of the genetic troublemakers before visible tumors even existed. This suggests that cancer's aggressive nature stems from molecular chaos that precedes detectable disease.…
